Jacqueline Waeni
Supervisors
Prof. James Nokes
Prof. James Nokes
Email : JNokes@kemri-wellcome.org James Nokes is Professor of Infectious Disease Epidemiology at the School of Life Sciences, University of Warwick. Since 2001 he has been based full time at the Wellcome Trust Major Overseas Programme, Kilifi coastal Kenya. James trained in Zoology (BSc) followed by a PhD in virus epidemiology. His principle interests are the transmission dynamics and control of human viral pathogens, including respiratory syncytial virus and rotavirus. The focus of his WT Senior Investigator Award is the integration of epidemiological and genomic data to infer transmission pathways at different scales of interest from the household to countrywide. His research group is inter-disciplinary using molecular, phylogenetic, immunological, mathematical, statistical and field approaches to address key questions relating to respiratory and enteric virus persistence, transmission, and intervention.
Dr. Charles Sande
I’m interested in applying modern systems tools to identify biomarkers of life-threatening infections in infants. Our studies are underpinned by a well-established demographic and health surveillance system that integrates comprehensive clinical, laboratory and demographic data for all infants who are admitted to hospital with severe infections as well as those with relatively mild infections. Using samples (nasal secretions, PBMC, serum and whole blood tempus RNA samples) collected from infants presenting with a broad spectrum of disease severity – ranging from life-threatening to mild infections – we employ a broad range of systems biology approaches – including proteomics, transcriptomics, metagenomics and systems serology – to identify biomarkers of life-threatening severe disease in infants.
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