Dr. Isabella Oyier

Current Mentees

John Muthii Muriuki Patience Kiyuka Akua Botwe

Past Mentees

Isabella completed her PhD in 2006 at the Liverpool School of Tropical Medicine and Hygiene on a Gates Malaria Partnership scholarship, in molecular and cell biology of Plasmodium falciparum. The project focused on the molecular characterization of the endocytic marker Rab5 in the parasite. She then joined the KEMRI Wellcome Trust Research Programme (KWTRP) on a 3 year postdoctoral research position working on studies of natural selection in Plasmodium falciparum merozoite antigen genes, with Prof Kevin Marsh and Dr David Conway. During this project she was involved in establishing the capillary sequencing facility at the unit and began to develop her career in the molecular epidemiology of malaria. She was awarded a 2 year re-entry grant from the Malaria Capacity Development Consortium (MCDC) in 2009 to conduct a longitudinal study on the genetic diversity of merozoite antigens. In 2012 she extended her interest to the genetic diversity of known human erythrocyte receptors involved in the invasion of the merozoite and conducted this work under an 18 month MCDC Initiative award. She is also carried out research on the temporal variation in malaria drug resistance markers in collaboration with Dr. Colin Sutherland at the London School of Hygiene and Tropical Medicine. She is based at the Centre of Biotechnology and Bioinformatics (CEBIB), University of Nairobi (UON), since 2011. Isabella was awarded a Wellcome Trust Intermediate Research Fellowship in 2016 to investigate the impact of polymorphisms on Plasmodium falciparum merozoite invasion of erythrocytes and on immune evasion. She continues to conduct studies on antimalarial resistance.