Timothy Chege
Supervisors
Dr. Charles Sande
Dr. Charles Sande
I’m interested in applying modern systems tools to identify biomarkers of life-threatening infections in infants. Our studies are underpinned by a well-established demographic and health surveillance system that integrates comprehensive clinical, laboratory and demographic data for all infants who are admitted to hospital with severe infections as well as those with relatively mild infections. Using samples (nasal secretions, PBMC, serum and whole blood tempus RNA samples) collected from infants presenting with a broad spectrum of disease severity – ranging from life-threatening to mild infections – we employ a broad range of systems biology approaches – including proteomics, transcriptomics, metagenomics and systems serology – to identify biomarkers of life-threatening severe disease in infants.
Dr. James Tuju
Chege holds a Bsc in Biotechnology & Biosafety from the University of Eldoret. He was first attached to the Kenya Agricultural Research Institute (KARI, Thika) as a student.
He then worked as a research assistant at the Gates Vaccine Project at the Msambweni County Referral Hospital where he was involved in daily routine assays targeting effective vaccine targets for various infections/diseases found in the coast.
He is currently a Post Graduate Diploma fellow/Intern at the KEMRI Wellcome Trust, Kilifi(In collaboration with Pwani University,Kilifi). His project aims to develop a modern platform for the diagnosis of acute infections using a synthetic peptide array approach. His research plays an important role in the possible development of a high throughput acute infection diagnosis method.
Timothy is passionate about immunology most specifically emerging B-cell novel functions in the adaptive immunity.
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