Prof. Anna Färnert

Affiliation(s):

Karolinska Institutet, Sweden

Prof. Faith Osier

Affiliations:

KEMRI – Wellcome Trust

Nuffield Department of Medicine, Oxford University

UniversitatsKilinikum Heildeberg

Faith trained as a clinician at the University of Nairobi, Kenya and obtained her MBChB degree in 1996. She immediately took up her Medical Internship at Coast General Provincial Hospital, in Kenya where she also worked as a Medical Officer in the department of Medicine until March 1998. Thereafter she took up a post as a Medical Officer/Research Officer at KEMRI-Kilifi, working in the Paediatrics Department of Kilifi District Hospital. It was here that she began to develop a career in research, engaging in clinical research studies and actively taking part in institutional academic meetings including weekly journal clubs and seminars. She subsequently specialized in Paediatrics, training both in Kenya and the United Kingdom, becoming a member of the Royal College of Paediatrics and Child Health UK in 2003 and a Consultant Paediatrician in Kenya in 2009. In 2004 she undertook a Masters in Human Immunity at the University of Liverpool, UK where she graduated with distinction, and was awarded a prize for being the best student of the year in the Department of Immunology. She has a PhD from the Open University, UK and currently works as a Clinical Research Fellow and Group Leader at the KEMRI-CGMR-C in Kilifi. She holds an Intermediate Fellowship in Public Health and Tropical Medicine from the Wellcome Trust, UK, and the prestigious MRC/DfID African Research Leader Award. In 2014 she was awarded the Young African Scientist Award by EVIMalaR, won the Merle A Sande Health Leadership Award and the Royal Society Pfizer Award. She is actively involved in capacity building for African Scientists and is building up a dynamic research group in Kilifi. Faith has been recently appointed Visiting Professor at the University of Oxford

Prof. James Kahindi

Email : jkahindi@pu.ac.ke

Dr. Eunice Nduati

Email : ENduati@kemri-wellcome.org

I joined the KEMRI Wellcome Trust Research Programme (KWTRP) in Nairobi working on antimalarial drug resistance. In 2005 I transferred to Kilifi to pursue my interest in the immunology of infectious diseases under the Biology and Pathology of the Malaria Parasite (BiolMalPar) Ph.D. training programme. This was a collaborative programme with time spent between the UK and Kenya. My thesis was on understanding host immune responses, specifically B-cell regulation in malaria. On returning to Kenya, I was awarded 6 months funding by BIOMALPAR/European Molecular Biology Laboratories (EMBL) a European Union Initiative to understand the role of soluble factors, such as the B cell activating factor (BAFF) on B-cell differentiation and function. I then successfully obtained a Wellcome Trust Training Fellowship, which supported my work on B-cell regulation in HIV infection and exposure. The aim of this work was to understand whether exposure to HIV virus or antigens, antiretroviral drugs and/or an altered placental cytokine milieu, in utero, affects the developing immune system in infants born to HIV infected mothers but are themselves not infected. In HIV infection, I have been involved in understanding B cell phenotypic and functional changes in HIV infected children. Currently I hold a mid-career fellowship with the IDeAL program at KWTRP and working within the International AIDS Vaccine Initiative (IAVI)-Vaccine Immunology Science and Technology for Africa (IAVI-VISTA) consortium, which has established longitudinal HIV cohorts. My work involves understanding adaptive immune responses, specifically T cell and B cell functions in early HIV infection and how this may impact on subsequent disease outcomes.

Dr. Isabella Oyier

Isabella completed her PhD in 2006 at the Liverpool School of Tropical Medicine and Hygiene on a Gates Malaria Partnership scholarship, in molecular and cell biology of Plasmodium falciparum. The project focused on the molecular characterization of the endocytic marker Rab5 in the parasite. She then joined the KEMRI Wellcome Trust Research Programme (KWTRP) on a 3 year postdoctoral research position working on studies of natural selection in Plasmodium falciparum merozoite antigen genes, with Prof Kevin Marsh and Dr David Conway. During this project she was involved in establishing the capillary sequencing facility at the unit and began to develop her career in the molecular epidemiology of malaria. She was awarded a 2 year re-entry grant from the Malaria Capacity Development Consortium (MCDC) in 2009 to conduct a longitudinal study on the genetic diversity of merozoite antigens. In 2012 she extended her interest to the genetic diversity of known human erythrocyte receptors involved in the invasion of the merozoite and conducted this work under an 18 month MCDC Initiative award. She is also carried out research on the temporal variation in malaria drug resistance markers in collaboration with Dr. Colin Sutherland at the London School of Hygiene and Tropical Medicine. She is based at the Centre of Biotechnology and Bioinformatics (CEBIB), University of Nairobi (UON), since 2011. Isabella was awarded a Wellcome Trust Intermediate Research Fellowship in 2016 to investigate the impact of polymorphisms on Plasmodium falciparum merozoite invasion of erythrocytes and on immune evasion. She continues to conduct studies on antimalarial resistance.

Dr. James Tuju